Baymax, a robot, plays a significant role in a story that revolves around two brothers. The setting is in San Fransokyo, a fictitious metropolis that combines San Francisco and Tokyo. The protagonist, Hiro Hamada, a gifted robotics expert, and his robot Baymax, investigate a criminal conspiracy. They collaborate with a squad of novice crime fighters such as Wasabi, Honey Lemon, GoGo Tomago, and Fred to solve the mystery related to the case.