Under the Tokugawa, a shogunate established order, enabling peace and relative prosperity among the citizens. However, the dark urges of humanity continue to awaken their greed, becoming a gateway for demons seeking possession of the mortal realm. It is Jonosuke's duty as the master of keys to exorcise these malevolent spirits. As the renowned locksmith of Edo, Jonosuke employs special locks to confine these wicked entities. Utilizing unorthodox methods, the enchanting O-kin joins him in his mission to face influential figures of the time, becoming valuable allies in thwarting a sinister plot looming over the upper echelons of the state.