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In this alternate universe portrayed by Tokyopop, individuals with animal-like abilities coexist with humans. Unfortunately, society rejects these enigmatic mutants known as +Anima. Four unique outcasts, including a boy with crow-like powers named Cooro, a fish-boy called Husky, a bear +Anima named Senri, and a girl named Nana who possesses the power of the bat, seek out others who share their condition while attempting to overcome societal prejudice towards anything deemed different.