A mysterious man creates chaos as he aggressively makes his way through a packed train car in Tokyo, leading to a series of puzzling events. Renji Amamiya, who has feelings for a woman named Toriko who works in the sex industry, is attacked by her but saved by Father Mitakura, a well-known exorcist. Father Mitakura informs Renji about the existence of demons, and together they work to solve the mysterious problems plaguing the city.